This article is a bit more in depth and requires a bit of biochemistry to fully understand but I wanted to add it to my posts because this was the article that turned my head and got me interested in ketogenics as a therapeutic aid to cancer treatments. It’s grounded in hard science.
Even if you don’t have a biochemistry or biology background I encourage you to read through and absorb what you can. As new immunotherapy treats begin replacing high toxic chemotherapies, these adjuvant therapies are going to become important.
Cancer cells, relative to normal cells, demonstrate significant alterations in metabolism that are proposed to result in increased steady-state levels of mitochondrial-derived reactive oxygen species (ROS) such as O2•−and H2O2. It has also been proposed that cancer cells increase glucose and hydroperoxide metabolism to compensate for increased levels of ROS. Given this theoretical construct, it is reasonable to propose that forcing cancer cells to use mitochondrial oxidative metabolism by feeding ketogenic diets that are high in fats and low in glucose and other carbohydrates, would selectively cause metabolic oxidative stress in cancer versus normal cells. Increased metabolic oxidative stress in cancer cells […]
Read the full article at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4215472/